Description

Buy JWH-210 chemical powder Online.

Buy JWH-210 Chemical Powder Online. JWH-210 (JWH-210 is also known as (4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone). Acts as a potent cannabinoid.

JWH-210 powder online

JWH-210 powder online is an analgesic chemical from the naphthoylindole family, which acts as a potent cannabinoid agonist at both the CB₁ and CB₂ receptors, with K_i values of 0.46 nM at CB₁ and 0.69 nM at CB₂. It is one of the most potent 4-substituted naphthoyl derivatives in the naphthoylindole series, having a higher binding affinity (i.e. lower K_i) at CB₁ than both its 4-methyl and 4-n-propyl homologues JWH-122 (CB₁ K_i 0.69 nM) and JWH-182 (CB₁ K_i 0.65 nM) respectively, and than the 4-methoxy compound JWH-081 (CB₁ K_i 1.2 nM).It was discovered by and named after John W. Huffman.

Pharmacological Drug Class: JWH-210 is an analgesic chemical from the naphthoylindole family and
acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors. It has Ki values of 0.46 nM at
CB1 and 0.69 nM at CB2. Of the first generation synthetic cannabinoids, it is one of the most potent 4-
substituted naphthoyl derivatives in the naphthoylindole series, having a higher binding affinity at CB1
than JWH-122, JWH-182, and JWH-081 (1).

Metabolism: Known metabolites of JWH-210 are JWH-210 N-pentanoic acid metabolite (detectable in
urine), JWH-210 N-(4-hydroxypentyl) metabolite (detectable in urine and serum), JWH-210 N-(5-
hydroxypentyl) metabolite (detectable in urine and serum), and JWH-210 5 hydroxyindole metabolite
(detectable in urine and serum). Hydroxylations on the napthoyl ring have also been reported (2).

Effects and Toxicity: User reports JWH-210 can be smoked after being sprayed on a plant material,
much like cannabis. Effects, start within 2-5 minutes of injestion. Little isknown about effects due solely to JWH-210 ingestion, but common effects from synthetic cannabinoids are alteration of mood and perception, panic attacks/agitation, cannabis-like high, and mild hallucinogens (visual and auditory).